Stroke in adult polycystic kidney disease.

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Stroke in adult polycystic kidney disease.

In order to assess the incidence of acute cerebrovascular events, 142 patients with adult polycystic kidney disease were retrospectively reviewed. Fourteen patients (9.8%) had 19 cerebral attacks. Six patients (4.2%) had intracranial haemorrhage attacks (three ruptured intracranial aneurysms and three cerebral haemorrhages). Ischaemic events occurred in nine patients (five cerebral infarctions ...

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In adult polycystic kidney disease (APKD), the cysts begin as tiny vesicles involving only one to two percent of the renal tubules.1 These "renegade" nephrons enlarge slowly but progressively, compressing and virtually obliterating the normal parenchyma, ultimately inducing renal insufficiency. This deterioration in function appears to accelerate in later life. A mathematical model of spherical...

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Ultrastructural tubular basement membrane lesions in adult polycystic kidney disease.

The pathogenesis of adult polycystic kidney disease (PCKD) remains an enigma. In an attempt to find a defect that might explain the cyst formation, an ultrastructural study was performed on seven fresh bilateral nephrectomies of seven patients suffering from adult PCKD. Marked electron microscopic changes of the tubular basement membranes were detected, including thickening, splitting, fraying,...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1992

ISSN: 0032-5473

DOI: 10.1136/pgmj.68.803.735